May 12, 2008...6:37 pm

Effect of vitamin E and selenium supplementation on oxidative stress status in pulmonary tuberculosis patients.

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The results of a recent study published in the journal, Respirology (2008), suggest that supplementation with selenium and Vitamin E may enhance antioxidant status in patients with pulmonary tuberculosis who are receiving standard medication treatment.

“BACKGROUND AND OBJECTIVE: Increased production of reactive oxygen species secondary to phagocyte respiratory burst occurs in pulmonary tuberculosis (TB). The present study evaluated the efficacy of vitamin E-selenium supplementation on oxidative stress in newly diagnosed patients treated for pulmonary TB.”

“The intervention group (n = 17) received vitamin E and selenium (vitamin E: 140 mg alpha-tocopherol and selenium: 200 microg).”

“CONCLUSION: A 2-month intervention with vitamin E and selenium supplementation reduces oxidative stress and enhances total antioxidant status in patients with pulmonary TB treated with standard chemotherapy.”

Reference:

Seyedrezazadeh E, Ostadrahimi A, Mahboob S, Assadi Y, Ghaemmagami J, Pourmogaddam M.  Effect of vitamin E and selenium supplementation on oxidative stress status in pulmonary tuberculosis patients.  Respirology. 2008 Mar;13(2):294-8.

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